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About this tool
Oxygenation ratio with Berlin ARDS severity categories.
Intended use
Patients with an arterial blood gas and known FiO₂.
Outcome
Oxygenation severity
Time horizon
Point in time
Limitations
- Depends on PEEP and FiO₂; categories assume PEEP ≥ 5 cmH₂O.
Clinical problems
Evidence
Evidence level
Strong evidence
Derived and externally validated in multiple cohorts (including prospective studies) and incorporated into major clinical guidelines. Methodology
Guideline status
Core oxygenation criterion of the Berlin ARDS definition (2012) and 2023 global definition.
Evidence summaries for this tool are awaiting independent clinical review. Statistics are shown only where they could be attributed to a specific publication.
References
- GuidelineARDS Definition Task Force; Ranieri VM, Rubenfeld GD, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA 2012;307:2526-2533. Find on PubMed (opens in a new tab)
- GuidelineMatthay MA, Arabi Y, Arroliga AC, et al. A New Global Definition of Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med 2024;209:37-47. Find on PubMed (opens in a new tab)
Version history
| Version | Formula | Effective | Reviewer | Changes |
|---|---|---|---|---|
| v1.0.0 | PaO2 ÷ FiO2; Berlin 2012 | 2026-10-03 | — | Initial implementation with reference test vectors. |
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Clinical decision support only. Interpret results in the context of the individual patient and current guidance; HumanPulse does not replace professional medical judgment.