Cytopenias and thrombosis

1. Step 1 · Hematology

   Absolute Neutrophil Count (ANC)

   Quantify neutropenia severity.

   Population

   Any CBC

   Key limitation

   Duffy-null phenotype.

   Inputs

   3

   Open tool

2. Step 2 · Hematology

   4Ts Score for Heparin-Induced Thrombocytopenia

   Thrombocytopenia on heparin — pretest probability of HIT.

   Population

   Heparin-exposed patients

   Key limitation

   Observer variability.

   Inputs

   4

   Open tool

3. Step 3 · Hematology

   PLASMIC Score for Thrombotic Thrombocytopenic Purpura

   Thrombotic microangiopathy — likelihood of TTP.

   Population

   Adults with TMA

   Key limitation

   Adults only.

   Inputs

   7

   Open tool

4. Step 4 · Hematology

   Iron Deficit — Ganzoni Formula

   Iron deficit for IV iron dosing.

   Population

   Iron-deficiency anaemia

   Key limitation

   Labels may use fixed dosing.

   Inputs

   4

   Open tool

The Navigator organises validated tools around a presentation. It does not recommend a diagnosis or treatment.