Hematology Equation Moderate evidence Clinical review pending v1.0.0

Absolute Neutrophil Count (ANC)

What is the absolute neutrophil count and is the patient neutropenic?

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About this tool

ANC from WBC and differential with conventional neutropenia severity bands.

Intended use

Any patient with a WBC differential.

Outcome

Neutrophil count

Time horizon

Point in time

Limitations

Severity thresholds do not account for Duffy-null associated neutrophil counts.

Clinical problems

Cytopenias and thrombosis

Evidence

Evidence level

Moderate evidence

Arithmetic; severity thresholds are consensus-based. Methodology

Evidence summaries for this tool are awaiting independent clinical review. Statistics are shown only where they could be attributed to a specific publication.

References

Review / updateBoxer LA. How to approach neutropenia. Hematology Am Soc Hematol Educ Program 2012;2012:174-182. Find on PubMed (opens in a new tab)

Version history

Version	Formula	Effective	Reviewer	Changes
v1.0.0	WBC × (segs + bands)	2026-10-03	—	Initial implementation with reference test vectors.

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Clinical decision support only. Interpret results in the context of the individual patient and current guidance; HumanPulse does not replace professional medical judgment.