Corrected Sodium in Hyperglycaemia
What will the sodium be once hyperglycaemia is corrected?
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About this tool
Sodium corrected for hyperglycaemia using both the Katz and Hillier factors.
Intended use
Patients with hyperglycaemia (e.g. DKA, HHS).
Outcome
Corrected serum sodium
Time horizon
Point in time
Limitations
- Both correction factors are approximations.
Clinical problems
Evidence
Evidence level
Moderate evidence
Externally validated, or an established physiological equation whose clinical thresholds rest on consensus; guideline support limited or mixed. Methodology
Evidence summaries for this tool are awaiting independent clinical review. Statistics are shown only where they could be attributed to a specific publication.
References
- Original publicationKatz MA. Hyperglycemia-induced hyponatremia — calculation of expected serum sodium depression. N Engl J Med 1973;289:843-844. Find on PubMed (opens in a new tab)
- Validation studyHillier TA, Abbott RD, Barrett EJ. Hyponatremia: evaluating the correction factor for hyperglycemia. Am J Med 1999;106:399-403. Find on PubMed (opens in a new tab)
Version history
| Version | Formula | Effective | Reviewer | Changes |
|---|---|---|---|---|
| v1.0.0 | Katz 1973; Hillier 1999 | 2026-10-03 | — | Initial implementation with reference test vectors. |
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Clinical decision support only. Interpret results in the context of the individual patient and current guidance; HumanPulse does not replace professional medical judgment.