Clinical tool library

Critical Care · Equation

S/F ratio

What is the non-invasive oxygenation ratio when no blood gas is available?

Moderate evidence Point in time

Nephrology · Equation

Cockcroft-Gault

What is the estimated creatinine clearance for drug dosing?

Moderate evidence Point in time

Nephrology · Equation

FENa

Is oliguric acute kidney injury more likely prerenal or intrinsic?

Moderate evidence Point in time

Nephrology · Equation

FEUrea

Is AKI prerenal in a patient receiving diuretics?

Limited evidence Point in time

Nephrology · Equation

KFRE

What is the 2- and 5-year risk of kidney failure in CKD G3–G5?

Strong evidence 2 and 5 years

Nephrology · Equation

CKD-EPI 2021

What is the estimated glomerular filtration rate?

Strong evidence Point in time

Hepatology · Equation

APRI

Is significant fibrosis or cirrhosis likely in chronic hepatitis?

Moderate evidence Point in time

Hepatology · Risk score

Child-Pugh

How severe is this patient's cirrhosis?

Moderate evidence 1–2 years (classically)

Hepatology · Equation

FIB-4

Does this patient likely have advanced liver fibrosis?

Strong evidence Point in time

Hepatology · Equation

MELD 3.0

What is the 90-day wait-list mortality risk in end-stage liver disease?

Strong evidence 90 days

Hepatology · Equation

Maddrey DF

Is alcohol-associated hepatitis severe enough to consider corticosteroids?

Moderate evidence ~30 days

Hematology · Risk score

4Ts

What is the pretest probability of heparin-induced thrombocytopenia?

Strong evidence Current episode

Hematology · Equation

ANC

What is the absolute neutrophil count and is the patient neutropenic?

Moderate evidence Point in time

Hematology · Equation

Iron deficit (Ganzoni)

How much parenteral iron does this patient need?

Limited evidence Point in time

Hematology · Risk score

PLASMIC

How likely is severe ADAMTS13 deficiency (TTP) in a patient with thrombotic microangiopathy?

Moderate evidence Current episode

Pulmonology · Equation

A–a gradient

Is hypoxaemia due to a gas-exchange problem or hypoventilation?

Moderate evidence Point in time

Pulmonology · Risk score

BODE

What is the long-term mortality risk in COPD?

Strong evidence ~4 years (median follow-up)

Endocrine & Metabolic · Equation

Anion gap

Is there an elevated anion gap metabolic acidosis?

Moderate evidence Point in time

Endocrine & Metabolic · Equation

Corrected sodium

What will the sodium be once hyperglycaemia is corrected?

Moderate evidence Point in time

Endocrine & Metabolic · Equation

HOMA-IR

What is the estimated insulin resistance from fasting glucose and insulin?

Limited evidence Point in time